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KMID : 0354720070310020175
Journal of Korean Diabetes Association
2007 Volume.31 No. 2 p.175 ~ p.179
A Typical Case of Fulminant Type 1 Diabetes Mellitus
Lee Jeong-Ho

Koh Gwan-Pyo
Yang Jung-Kyung
Kim Ki-Hong
Lim Dong-Mee
Park Keun-Young
Abstract
Recently type 1 diabetes with acute onset and no evidence of islet autoantibodies have been showed as
"fulminant type 1 diabetes" and as novel subtype of type 1B diabetes. The study was made progress in
Japan. We report a typical case of fulminant type 1 diabetes.
A 24 years old male to be in good condition visited our hospital because of flu-like symptom, diarrhea, and
abdominal discomfort. He has no medical history and family history of diabetes. The level of plasma glucose
is 962 mg/dL, serum ketone body 5.8 mmol/L, arterial blood pH 7.111 and he was diagnosed as diabetic
ketoacidosis. Anti-GAD antibody and islet cell antibody were negative and HbA1c is 5.5%. All of them were
compatible with the diagnostic criteria of fulminant type 1 diabetes.
After the patient has been treated with insulin, his symptoms were improved and abnormal laboratory data
were normalized. We report this case with a review of the literature.
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